LOLA

Region-seq enrichment analysis

LOLA

Genomic datasets are often interpreted in the context of large-scale reference databases. One approach is to identify significantly overlapping gene sets, which works well for gene-centric data. However, many types of high-throughput data are based on genomic regions. Locus Overlap Analysis (LOLA) provides easy and automatable enrichment analysis for genomic region sets, thus facilitating the interpretation of functional genomics and epigenomics data.

Publication

LOLA: Enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor

LOLA: Enrichment analysis for genomic region sets and regulatory elements in R and Bioconductor

Sheffield NC, Bock C

Bioinformatics  32, 587-589 (2016). DOI: 10.1093/bioinformatics/btv612

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* shared first or shared senior authorship