RnBeads

DNA methylation analysis

RnBeads

RnBeads is an R package for comprehensive analysis of DNA methylation data obtained with any experimental protocol that provides single-CpG resolution. Supported assays include Infinium and EPIC microarrays and bisulfite sequencing protocols, and also MeDIP-seq and MBD-seq once the data have been preprocessed with DNA methylation level inference software. RnBeads implements an analysis workflow that is significantly more comprehensive than those of existing tools. It documents its results in a highly annotated and readable hypertext report, and it scales to the large sample sizes that are becoming the norm for DNA methylation analysis in human cohorts.

Publications

RnBeads 2.0: comprehensive analysis of DNA methylation data

RnBeads 2.0: comprehensive analysis of DNA methylation data

Müller F*, Scherer M*, Assenov Y*, Lutsik P*, Walter J, Lengauer T, Bock C

Genome Biology  20, 55 (2019). DOI: 10.1186/s13059-019-1664-9

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Comprehensive analysis of DNA methylation data with RnBeads

Comprehensive analysis of DNA methylation data with RnBeads

Assenov Y*, Müller F*, Lutsik P*, Walter J, Lengauer T, Bock C

Nature Methods  11, 1138-1140 (2014). DOI: 10.1038/nmeth.3115

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* shared first or shared senior authorship